Expert entrepreneurs dedicated to changing the world of cancer detection and saving more patients’ lives

The AOA Dx team is reimagining the future of early cancer detection

The AOA Dx founding team has worked together for over a decade at two successful women’s health diagnostic startups, both resulting in strategic exits. With more than 30 years of experience bringing products from concept to commercialization across global markets, they’ve assembled a unique team of experts in the field who are dedicated to changing the world of oncology.

Founders

Oriana Papin-Zoghbi

Position: Chief Executive Officer & Co-Founder
Categories: Founders

Oriana is a visionary leader in the field of women’s health and diagnostics. Recently honored in Inc’s 2022 Top 100 Female Founders for her work in ovarian cancer diagnosis, Oriana brings a wealth of knowledge and expertise bringing disruptive diagnostics to market and changing the landscape of clinical practice. Oriana is passionate about entrepreneurship and problem solving and hopes to use these skills to revolutionize early cancer detection, particularly in cancers that disproportionately affect women.

Oriana has global experience creating and leading organizations resulting in successful strategic exits. Prior to AOA, she led teams at early-stage startups and large life sciences companies. Oriana has a track record of developing a highly productive culture and turning visions into reality. She has a proven technical record of creating market entry strategies and product launches in new markets, including launching nationwide HPV screening in East Africa and novel diagnostics in maternal fetal medicine, oncology and infectious diseases.

As CEO of AOA, her dedication and work have earned her numerous awards and recognition, including the Massachusetts Life Sciences Center MassNextGen Award, The Eddies People’s Choice Award and The Wave Summit’s Emerging Women Founder in Bio Award.

Oriana holds a degree from Boston University in Economics and International Relations, and she has experience both living and working in various geographies.

Oriana Papin-Zoghbi

Chief Executive Officer & Co-Founder

Alex Fisher

Position: Chief Operating Officer & Co-Founder
Categories: Founders

Alex is a passionate and dedicated business leader with a track record of launching UK medical device and diagnostics sales companies. He has​ extensive experience priming markets, launching products and driving early product sales.​

In most recent roles, Alex has been committed to commercializing and launching innovative, disruptive products through his own businesses across European healthcare markets with a primary focus on obstetrics and gynecology.​​

Alex works closely with Oriana, ensuring strategies relating to finance, accounting, legal and fundraising are executed in a timely manner. On a daily basis, Alex ensures AOA’s operations are running smoothly and efficiently.

Alex has a degree and MSc from the University of Southampton and University College London.

Alex Fisher

Chief Operating Officer & Co-Founder

Anna Jeter

Position: Chief Regulatory Officer & Co-Founder
Categories: Founders

Anna is an innovator and a dynamic business leader with a passion for advancing healthcare through world-class diagnostics.​ As the Chief Reglatory Officer of AOA, she is pioneering the development of the groundbreaking GlycoLocateTM platform for early cancer detection by utilizing tumor marker gangliosides and AI to solve some of the most difficult challenges in diagnostics today.

Anna was named to Inc. Magazine’s 2022 Female Founders 100 List. She brings a wealth of experience to AOA having overseen the inclusion of multiple products into national and pan-European guidelines, and she has experience with US FDA submissions for 510(k), PMA, and CLIA LTD regulatory routes.​

Anna has a unique global perspective on healthcare having led teams launching paradigm changing diagnostics in women’s health in Europe, the Middle East, Latin America and Asia.

Anna Jeter

Chief Regulatory Officer & Co-Founder

Team

Adele Blackler, Ph.D.

Position: Vice President of Platform Development
Categories: Team

Adele has extensive experience in mass spectrometry, oncology liquid biopsy tests and clinical proteomic applications. For the past decade, she has worked at multiple diagnostic companies developing multiplex biomarker tests to support therapeutic decisions for solid tumor treatment, including lung, colorectal and breast cancer. She has worked on single site Laboratory Developed Tests using both proteomic and genomic platforms and Clinical Trial Assays as companion diagnostics for guiding lung cancer therapy.

Adele received her bachelor’s in chemistry from the Colorado school of mines and received her Ph.D. from the University of Colorado, at Anschutz, where she developed high-throughput proteomic methods for membrane proteins. Her post-doctoral fellowship was at the National Cancer Institute developing methods to combine high throughput protein analysis with tissue microdissection.

As Vice President of Platform Development, Adele oversees development of new assays for the detection and quantitation of gangliosides to identify disease signatures.

Adele Blackler, Ph.D.

Vice President of Platform Development

Andrea Cioffi

Position: Director of Business Operations
Categories: Team

Andrea is a passionate leader who excels at scaling up systems and solutions to create positive outcomes for community stakeholders.

Having graduated from the Boston University Questrom School of Management with a degree in Marketing, she was a 2009 Teach for America Corps member, serving in Chelsea MA.

After spending 13 years working in charter and turnaround schools as a school leader she has pivoted to ensuring behind the scenes operations at AOA Dx run smoothly in order to accomplish our mission critical goals.

While she has worked for AOA part time since 2020, she is excited to support the team full time in finance, HR, marketing, and project management.

Andrea Cioffi

Director of Business Operations

Elizabeth Yarber

Position: Director of Clinical Operations
Categories: Team

Elizabeth is a clinical research professional specializing in the management of clinical operations, quality, and regulatory oversight of global clinical trials in multiple therapeutic areas in biopharmaceutical, medical device and diagnostics.​

Elizabeth has extensive experience in all phases of clinical trials that allowed market access for strategic business initiatives. She is Project Management certified through PMI and has been involved in the clinical trial process from development to regulatory approval applying a strong focus on risk and quality oversight.

As Director of Clinical Operations, Elizabeth has overall responsibility for leading AOA’s clinical study operations.

Elizabeth holds an undergraduate degree in Organizational Leadership and a MSc. in Health Outcomes Research from St. Louis University.

Elizabeth Yarber

Director of Clinical Operations

Abby Tyler

Position: Head of Immunoassay R&D

Categories: Team

Abby is an experienced leader in the field of immunoassay development. Throughout her career, she has developed and overseen the creation of numerous immunoassays, resulting in a deep and comprehensive expertise in the field. Abby’s passion for problem-solving and curiosity has been pivotal in driving her approach to assay development. She excels at tackling complex challenges and applies her analytical thinking skills to develop creative solutions and products.

Prior to joining AOA Dx, Abby led multiplexed immunoassay development projects that became widely utilized research products, making contributions to global health and the advancement of disease understanding. At AOA Dx, she is utilizing her skills to develop AOA’s ovarian cancer diagnostic tests, leveraging her extensive knowledge and experience in the field.

Abby holds degrees in Chemical and Biological Engineering from Utah State University and University of Colorado at Boulder.

Abby Tyler

Head of Immunoassay R&D

Robert Law, Ph.D.

Position: Immunoassay Scientist

Categories: Team

Robert is an industrious molecular and cell biology expert with more than a decade of experience conducting research in the areas of biopharmaceutical engineering, genome editing, and cancer cell biology. He has utilized his proficiency in these areas to execute product development strategies within the gene editing space in addition to spearheading research efforts to delineate complex cell signaling pathways for the identification of diagnostic and therapeutic targets to combat cancer. His work has resulted in several publications in Science Advances, Science Signaling, Journal of Cell Biology, and Cancer Research.

As an innovative and dynamic scientist, Robert is committed to solving challenging problems centered around cancer diagnostics and prevention. At AOA Dx, he is using his skills and expertise to develop AOA’s ovarian cancer diagnostic test in conjunction with expanding the GlycoLocate™ platform to enable the detection of additional cancer targets.

Having earned his Ph.D. from Johns Hopkins University in Chemical and Biomolecular Engineering, Robert also holds a B.S. from The Ohio State University in the same discipline graduating “With Research Distinction”.

Robert Law, Ph.D.

Immunoassay Scientist

Rachel Culp-Hill, Ph.D.

Position: Mass Spectrometry Scientist
Categories: Team

Rachel is an accomplished expert in metabolomics with over 10 years of mass spectrometry experience. Her previous research focused on studying metabolic alterations in various disease states, including acute myeloid leukemia, Down Syndrome, sickle cell disease, breast cancer, and hemorrhagic shock. Her groundbreaking work on understanding the complex metabolome of acute myeloid leukemia stem cells and other cancers has been published in scientific journals such as Nature Medicine, Nature Cancer, Cell, Cancer Cell, Cell Stem Cell, Blood, and more.

At AOA Dx, Rachel dedicates her expertise to validating a diagnostic test for ovarian cancer and expanding the GlycoLocateTM platform to detect additional cancer targets. Her commitment to cancer diagnostics and prevention fuels her drive to solve challenging problems in the field.

Rachel earned her Ph.D. in Biochemistry from the University of Colorado Anschutz Medical Campus and holds an M.Sc. in Microbiology from the University of Florida, along with a B.S. in Biochemistry and Molecular Biology from Michigan State University. With her multidisciplinary knowledge, scientific acumen, and proven track record, Rachel continues to push the boundaries of cancer research, contributing to advancements in detection and treatment methods.

Rachel Culp-Hill, Ph.D.

Mass Spectrometry Scientist

Enkhtuya Radnaa, Ph.D.

Position: Immunoassay Associate Scientist
Categories: Team

Dr. Enkhtuya Radnaa, MS., Ph.D., is an experienced Molecular and Cellular Biology Scientist with a decade-long journey in the field. Her cancer-related research journey began at the Cancer Research Institute, Kanazawa University, Japan, where she earned her Ph.D. and pursued postdoctoral research. Expanding upon her expertise in cancer research, Dr. Enkhtuya Radnaa embarked on a new phase of her career in obstetrics and gynecology within the University of Texas Medical Branch (UTMB) research division. As a faculty member specializing in molecular and cellular biology, she took the lead on groundbreaking projects. Notably, she was instrumental in developing immortalized cell lines derived from human placental tissues and conducted intricate gene manipulations within these cell lines. These cell lines have proven to be invaluable assets, playing a pivotal role in advancing organ-on-chip-based research initiatives. Dr. Enkhtuya Radnaa’s efforts in this regard have been supported by multiple NIH-funded grants, including those provided by NCATs and the Superfund research programs. Her innovative work has significantly contributed to the ongoing progress of research at the intersection of molecular biology and women’s health, helping to advance our understanding of critical aspects of human reproduction and development. Her research in understanding the molecular mechanisms underlying preterm birth studies garnered recognition. Dr. Enkhtuya Radnaa received the prestigious “Best New Investigator” award in 2022 from the Society for Reproductive Investigation for her contributions to furthering the Society’s objectives in women’s health. Enkhtuya’s unwavering dedication to scientific exploration is evident in her contributions to publications, including those featured in Science Advances, Lab on a Chip, Clinical Science, and Biology of Reproduction journals.

Enkhtuya Radnaa, Ph.D.

Immunoassay Associate Scientist

Chloe Talley

Position: Clinical Trials Associate
Categories: Team

Chloe Talley is joining AOA Dx as a Clinical Trial Associate (CTA). While getting her undergraduate degree at Virginia Tech (VT) in Public Relations and Marketing she worked part time as a PR & Marketing Intern at ProActive Communications which focused on strategic communications and firm specialization in public affairs, public relations, and video productions. She also worked as Executive Producer at Real America’s Voice which delivered news programs and live-event coverage that captured authentic voice and passion from people across America. Through both opportunities she learned the essential pieces of client engagement and stakeholder responsiveness. After graduating from VT in May 2022 she became a Technical Recruiter where she was exposed to several industry leaders such as telecom, financial services, healthcare, public sector, transportation, and travel. She also served as the subject matter expert and primary point of contact for client candidacy needs among client and business stakeholder networks which will allow her to support AOA Dx in their clinical study efforts. She feels inspired to be a part of a company that honors the importance of revolutionizing women’s health.

Chloe Talley

Clinical Trials Associate

Advisors

Prof. Uri Saragovi, PhD

Position: Chief Scientific Officer
Categories: Advisors

Dr. Saragovi is a passionate and world-leading scientist in the area of Translational Medicine.

Dr. Saragovi has published over 200 publications and 21 patents, primarily focusing translational medicine. More recently Dr. Saragovi has focused on the targeting of gangliosides, which are used clinically for cancer diagnosis, prognosis, and therapy.

Dr. Saragovi based at McGill University and Lady Davis Institute at the Jewish General Hospital, Montreal.

Prof. Uri Saragovi, PhD

Chief Scientific Officer

Surbhi Sarna

Position: Independent Board Member
Categories: Advisors

Surbhi Sarna is the founder and former CEO of nVision medical, a medical device company that, to date, is the only device cleared by the FDA to collect cells from the fallopian tube for the detection of ovarian cancer. Having led the company from inception, nVision Medical was acquired by Boston Scientific in 2018 for $275m.

Most recently Surbhi became Y Combinator’s first-ever partner for healthcare and biotech, and she currently sits on the board of Penumbra, Progenity, Astia, Draper University and the Harker School. Surbhi has extensive experience with early product development, funding, clinical trials and commercialization.

Surbhi Sarna

Independent Board Member

Elizabeth Garner

Position: Clinical Advisor
Categories: Advisors

Elizabeth Garner, MD, MPH has over a decade of pharmaceutical development experience. She also has deep expertise in clinical trial design and execution. She has held roles of increasing strategic responsibility in large and small companies, including ObsEva SA, Merck, Abbott (AbbVie), Myriad Genetics, and Agile Therapeutics. In addition to Pharm-Olam, she is also on the Boards of the Drug Information Association (DIA) and the American Medical Women’s Association (AMWA), and she was a 2019 awardee of the PharmaVoice 100 most inspiring individuals in the life-sciences industry.

Dr. Garner is currently the Chief Scientific Officer at Ferring Pharmaceuticals, a biopharmaceutical company that focuses on the development of innovative products in the areas of reproductive medicine and maternal health, urology and gastroenterology. Dr. Garner received joint MD and MPH degrees from Harvard Medical School and the Harvard School of Public Health. She was trained in obstetrics and gynecology at Brigham and Women’s/Massachusetts General Hospitals and completed a fellowship in gynecologic oncology at Brigham and Women’s and Dana Farber Cancer Institute.

Elizabeth Garner

Clinical Advisor

Amy P.N. Skubitz, Ph.D.

Position: Clinical Advisor
Categories: Advisors

Amy P.N. Skubitz, Ph.D. is a Professor in the Department of Laboratory Medicine and Pathology at the University of Minnesota (UM) and an Adjunct Professor in the Department of Obstetrics, Gynecology, and Women’s Health. Dr. Skubitz serves as the Director of the Ovarian Cancer Early Detection Program (OCEDP) at the UM.

Her research interests include the progression and recurrence of ovarian cancer, which involves its genetic profile and the discovery of new biomarkers by mass spectrometry-based proteomics using a wide variety of biospecimens. Her research studies represent an approach toward understanding the molecular mechanisms modulating the phenotypic behavior of cancer cells with the ultimate goal of designing biomarkers and/or biopharmaceuticals for therapeutic use in cancer.

As a faculty member at the UM for the past 30 years, Dr. Skubitz’s research has been continually funded from a variety of sources. She has published over 125 manuscripts in the field of cancer. She has overseen and supervised many projects with collaborators at the UM, nationally, and internationally.

She established the UM’s Tissue Procurement Facility and served as the Director or Assistant Director for 15 years. She has been a member of the International Society for Biological and Environmental Repositories since 1999, and served on the Education and Training Committee for 6 years.

She has been a mentor to many faculty, postdoctoral fellows, graduate students, undergraduates, and technicians who have performed research projects in her laboratory.

Amy P.N. Skubitz, Ph.D.

Clinical Advisor

Kevin Elias

Position: Clinical Advisor
Categories: Advisors

Dr. Kevin Elias is an experienced physician-scientist with a demonstrated history of success in translational medicine and advanced oncologic care. He has years of experience in Medical Education, Clinical Trials & Healthcare Leadership for gynecologic oncology and early cancer detection. Graduating from Harvard College and Vanderbilt University School of Medicine, he completed his residency in OB/GYN at Brigham and Women’s Hospital and fellowships is Gynecologic Oncology and Anesthesia Critical Care Medicine at Brigham and Women’s Hospital. Additionally, he conducted post-doctoral research at Dana-Farber Cancer Institute in molecular biology and MIT in cancer nanotechnology. He is currently an active practicing physician and Director of the Gynecologic Oncology Laboratory at Brigham and Women’s Hospital.

Kevin Elias

Clinical Advisor

Larry Kessler, Sc.D.

Position: Clinical Advisor
Categories: Advisors

Dr. Kessler is Professor in the Department of Health Systems and Population Health, University of Washington, which he chaired from 2009 – 2015. He has over 40 years of experience in health services research, including positions at the National Institute of Mental Health, National Cancer Institute, and FDA. At NCI, he and his colleagues substantially changed the way in which cancer surveillance is performed, with the addition of the Cancer supplements to the National Health Interview Survey, the SEER-Medicare data system, and the Breast Cancer Screening Consortium and the Breast Cancer Surveillance Consortium. His research record includes focused work in cancer, cancer surveillance research, and regulatory aspects of medical products. He came to UW from U.S. FDA Center for Devices and Radiological Health. His recent collaborative research focuses on patient centered outcomes and comparative effectiveness research. He also serves as Deputy Chair of the MCED Consortium.

Larry Kessler, Sc.D.

Clinical Advisor

Awards and Accelerators